Fasting Boosts Health

Various versions of the intermittent fasting diet appear to have weight loss benefits. A new study investigating why they work concludes that circadian rhythms are key.

Intermittent fasting has become popular, but how does it work?

While the modern world appears awash with fad diets, people seem to be giving a fair bit of attention to intermittent fasting.

As its name implies, intermittent fasting involves eating nothing for extended periods of time.

Some studies have found that this type of diet is beneficial, but exactly why it benefits health is not yet clear.

Recently, a group of scientists at the University of California, Irvine investigated the impact of fasting on our circadian clock.

Daily sleep–wake cycles, or circadian rhythms, drive the ebb and flow of human life; they control much more than just our sleepiness levels. Our 24-hour cycles involve metabolic, physiological, and behavioral changes that impact every tissue of the body.

Perhaps the most well-known way to influence the clock is via exposure to bright lights, but this isn’t the only way; food intake also impacts the clock.

We are slowly beginning to understand how eating plays a role in modulating circadian rhythms, but we know even less about how a lack of food might affect rhythms.

Fasting and circadian rhythms

The authors of the new study were particularly interested in learning about how fasting influenced circadian rhythms in the liver and skeletal muscles. The researchers published their findings in the journal Cell Reports.

Fasting is a natural phenomenon for most animals, because food is not always readily available. In times of hardship, certain metabolic changes occur to allow the body to adapt.

For instance, when glucose is scarce, the liver begins to create ketones from fatty acids, which the body can use as an emergency energy source.

A host of fasting-induced transcription factors drive these metabolic changes. These transcription factors also seem to influence circadian rhythms.

As an example, one study split mice into two groups; the researchers put one on an intermittent fasting regime, and they allowed the second to eat whenever it liked.

Both groups consumed the same amount of fat and calories; however, despite having the same energy intake, mice in the fasting group did not develop obesity or metabolic disorders as the other mice did.

Also, importantly, the authors noted that the animals’ circadian oscillations were more robust in the fasting group.

As the authors of the recent study point out, “[F]asting appears to be a strong metabolic cue to entrain rhythmic gene expression.”

Scientists believe that having more clearly defined cycles might be part of the reason that fasting promotes good health.

Rhythmic fasting genes

The most recent study also involved mice. While the animals adhered to 24-hour periods of fasting, the scientists measured various physiological functions.

They saw that while fasting, mice used less oxygen and energy. However, as soon as the mice ate, these gene-driven physiological changs were reversed. This mirrors what researchers have previously seen in humans.

Lead study author Prof. Paolo Sassone-Corsi explains what the researchers found, saying, “We discovered [that] fasting influences the circadian clock and fasting-driven cellular responses, which together work to achieve fasting-specific temporal gene regulation.”

They also note that it influenced different tissue types to different degrees. As Prof. Sassone-Corsi says, “Skeletal muscle, for example, appears to be twice as responsive to fasting as the liver.”

How might this benefit us?

Having assessed the gene changes that occur with fasting, the scientists now need to explain how they might benefit health.

Prof. Sassone-Corsi suggests that “the reorganization of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression.”

He adds, “In other words, fasting is able to essentially reprogram a variety of cellular responses. Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefitting health and protecting against aging-associated diseases.”

Over the years, it has grown increasingly clear that disrupting circadian rhythms can increase the risk of obesity and metabolic disorders, such as diabetes. This new work brings us closer to understanding why that might be.

Though understanding the influence of fasting on circadian rhythms and gene expression is still in its infancy, the authors hope that one day, their work will help find the optimum fasting regime for health.

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Succeed or Fail on the Keto Diet…

What Makes the Difference Between People Who Succeed and Failon the Keto Diet

Two women, both 41-years-old with young children at home, decided to try the Keto diet.

The first woman was strict and did well the first week. She ate properly and got into ketosis. She even lost a few pounds that first week.

But in the second week she went out to eat. She did so well the first week, she decided to cheat. She drank a margarita… and it was downhill from there.

She felt guilty about her failure and continued to break her Keto diet the rest of the week. By week three, she was back to her old ways and telling people she tried Keto, but it didn’t work.”

What the 2nd Woman Did…

Like the first woman, the second woman was also strict the first week and lost a few pounds. She was encouraged.

She also went out to eat, but somehow found the willpower to stick with Keto food choices. In week two, she lost even more weight. In the span of 14 days, she’d lost 11 lbs and counting.

Her kids noticed. Her husband noticed. Her friends asked her what she was doing differently.

The second woman never slipped up, and by the end of four weeks had lost 21 lbs. She was noticeably slimmer, was sleeping better, had much more energy, and was feeling the best she’d felt in years.

So What Made the Difference?

Most people who try a new diet do it without a plan.

They understand the rules: the foods they can and can’t eat. They even have a variety of quality recipes at their fingertips.

But what they DON’T have is a day-by-day plan to carry them through that critical first month.

Without a plan, it’s easy for them to be swayed by peer pressure. It’s easy for them to be unprepared… and then make bad decisions just because it’s easier.

That’s why we put together…

The 28-Day Keto Challenge

The 28-Day Keto Challenge is a well-crafted plan to get you through the first month.

You get a 28-day meal plan to guide you every step of the way. You’re never left to figure things out on your own. Nothing is left to chance.

Simply follow the plan and you WILL succeed.

And it’s more than a plan. It’s also a challenge. It’s designed to stretch you, to see what you’re really capable of.

(Not to worry… With the proper guidance, you can do more than you think!)

When you sign up for the 28-Day Keto Challenge, you’ll get a full 28-Day Meal Plan, which includes 7 guides to educate and encourage you on the way…

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Keto Diet: The Basics

To get started, you’ll learn the basics of the keto diet, including how it was developed, how it works, and who it’s best for. You’ll learn the 11 benefits of the Keto diet and you’ll get a handy “Keto food pyramid” with shopping list.

Last but not least, you’ll get 13 tips for success, a list of foods you can enjoy, and a list of foods to avoid.

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Eating on Keto

In this guide, you’ll 10 breakfast recipes, 14 lunch recipes, and 14 dinner recipes. You’ll also get snack options and tips for understanding and conquering your cravings.

The Eating on Keto guide comes with a companion 28-Day Meal Plan calendar, which shows you what to eat for every meal for a full 28 days. All the meals on the calendar are in this guide!

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Ketosis: Tips for Staying in Ketosis

This guide focuses on what ketosis is and how your body changes when you enter ketosis.

You’ll learn how to smoothly transition into ketosis in as little as 3 days, how to know for sure if you’re in ketosis, when to cycle out of ketosis, and much more.

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Macros: A Micro Look at Macronutrients

“Knowing your macros” is something you’ll hear a lot on the Keto diet. Put simply, you need to know how many grams of fat, protein, and carbs you’re eating each day.

This guide will teach you how to calculate your macros and maintain the proper ratios to stay in ketosis. You’ll also learn about “hidden carbs” to look out for!

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Keto Flu: Beating It in a Healthy Way

Not everybody experiences the “Keto flu” when their bodies transition into ketosis, but some do. Fortunately, it’s a temporary short-term experience.

Even better, you can reduce “Keto flu” symptoms and make them go away by following the advice in this useful guide.

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Intermittent Fasting: Tips for Success

Intermittent Fasting (or I.F. for short) can be a useful tool for Keto dieters. In this guide, you’ll learn what intermittent fasting is, the health benefits it can provide you, as well as 5 different styles of I.F. you can try.

Note: Intermittent Fasting is not a requirement on the Keto Diet. But it can kickstart ketosis and accelerate fat loss.

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Keto and Friends
Dealing with Social Pressures

As you probably know, one of the biggest obstacles to success on ANY diet is peer pressure and negative feedback from friends and family.

This guide will provide you with healthy ways of dealing with these social pressures. It also includes a handy chart with tips for eating out and some guidelines for drinking alcohol.

When You Complete Your 28-Day Keto Challenge, You’ll Feel a HUGE Sense of Accomplishment!

Just imagine… 28 days from now, you will have successfully completed the Keto Challenge.

Not only will you feel a huge sense of accomplishment, you’ll:

  • Be lighter and thinner (it’s not uncommon to lose 20+ lbs!)
  • Have more energy than you’ve felt in years
  • Be sleeping better and feeling more rested when you wake up
  • Notice improvements in your skin and hair

Probably best of all, you’ll have MOMENTUM to keep going with your new Keto lifestyle.

TO HELP YOU GET THROUGH YOUR 28-DAY KETO CHALLENGE, WE’VE ALSO GOT 3 BONUS GIFTS FOR YOU…

Add fun and variety to your Keto diet with these super low-carb treats everyone will enjoy — even non keto dieters!